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IndicationsThe management of grand mal and psychomotor (temporal lobe) epilepsy. It is also of value in the management of focal or Jacksonian seizures myoclonic jerks and akinetic attacks.Dosage and AdministrationTreatment must always be individualised. In many patients it will be possible to use APO-PRIMIDONE alone but in some it will need to be combined with other anti-convulsants.APO-PRIMIDONE is usually given twice daily. Start with 125mg once daily late in the evening. Every three days increase the daily dose by 125mg until the patient is receiving 500mg daily. Thereafter every three days increase the daily dose by 250mg in adults or 125mg in children under 9 years of age until control is obtained or the maximum tolerated dosage is being given. This may be as much as 1 500mg per day in adults and 1 000mg per day in children.Average daily maintenance doses:Children up to 2 years: 250mg to 500mg per dayChildren 2 to 5 years: 500mg to 750mg per dayChildren 6 to 9 years: 750mg to 1 000mg per dayAdults and children over 9 years: 750mg to 1 500mg per day.The total daily dose is usually best divided and given in two equal amounts - one in the morning and the other in the evening. In certain patients it may be considered advisable to give a larger dose when seizures are more frequent e.g. if the attacks are nocturnal then all or most of the day's dose may be given at night; if the attacks are associated with some particular event such as menstruation a slight increase at the appropriate time is often beneficial.
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About Apo Primidone Mysoline:
Product Type: Prescription Drugs 2
Apo-Primidone ( Mysoline Generic Primidone )
Apo-Primidone (Mysoline Generic Primidone)
Mysoline Generic Primidone
250mg 100 Tablets 200(2 x 100) Tablets
Mysoline Generic Primidone Apo-Primidone

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Pharmacy:
Dozens of patents for name-brand drugs are due to expire within the next 14 months, and generic drugs will replace some of the most popular and widely advertised drugs used today. For millions of people worldwide, this means switching from familiar brands like Lipitor to generic equivalents. How will this affect drug companies, and what will be the impact on people who depend on expensive prescription medication? Here, a brief guide:
Which drugs are scheduled to go generic?
Some real blockbusters. "In the next two years, six of the 10 top-selling drugs will lose their patents," says Chris Woolston in the Los Angeles Times. Lipitor, the world's best-selling drug, which is used to lower cholesterol, will be available as a generic in November of this year. Another best-seller, the blood thinner Plavix, will lose its patent in May 2012. Other well-known drugs with expiring patents include the arthritis treatment Enbrel, the anti-psychotic Zyprexa, as well as drugs for bipolar disorder, HIV, high cholesterol, and other conditions.


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