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COLOSPA Colofac

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Category : Antispasmodic; smooth muscle relaxant. Mebeverine has a direct non-specific relaxant effect on vascular cardiac and other smooth muscle. Studies indicate that the spasmolytic activity of mebeverine is not restricted to one particular system but the compound possesses a polyvalent spasmolytic action in which at least three types of mechanisms are involved:- a direct musculotropic action involving calcium ion exchange and stabilization of excitable membranes- a competitive antimuscarinic activity of about 0.05 - 0.1 times that of atropine- a local anaesthetic activity together with potentiation of sympathetic inhibitory influences due to blockade of noradrenaline uptake into sympathetic nerve endings

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Product Type: Prescription Drugs 4

COLOSPA ( Colofac Generic Mebeverine )

COLOSPA (Colofac Generic Mebeverine)

Colofac Generic Mebeverine

135mg 135mg Tabs 4 x 100 Tablets 100 Tablets 2 x 100 Tablets 30 (3 x 10) Colofac Generic Mebeverine COLOSPA

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Pharmacy: Dozens of patents for name-brand drugs are due to expire within the next 14 months, and generic drugs will replace some of the most popular and widely advertised drugs used today. For millions of people worldwide, this means switching from familiar brands like Lipitor to generic equivalents. How will this affect drug companies, and what will be the impact on people who depend on expensive prescription medication? Here, a brief guide: Which drugs are scheduled to go generic? Some real blockbusters. "In the next two years, six of the 10 top-selling drugs will lose their patents," says Chris Woolston in the Los Angeles Times. Lipitor, the world's best-selling drug, which is used to lower cholesterol, will be available as a generic in November of this year. Another best-seller, the blood thinner Plavix, will lose its patent in May 2012. Other well-known drugs with expiring patents include the arthritis treatment Enbrel, the anti-psychotic Zyprexa, as well as drugs for bipolar disorder, HIV, high cholesterol, and other conditions.